Does retinol in skincare even work?

Published 2023-11-06
Does the best skincare ingredient even work? Some scientists and dermatologists say there's no trustworthy scientific evidence to back up retinol. Let's look at the evidence for retinol, and why skincare science might look a bit sketchy.

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0:00 The case against retinol
1:04 What is retinol?
2:35 The dang government
4:33 Why isn't retinol a drug?
5:34 Cash Rules Everything Around Me
10:24 The evidence for retinol
15:11 What about other ingredients?

How to start on retinoids:    • How to Start on Retinoids | Lab Muffi...  
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🙋🏻 I'm Michelle, a chemistry PhD, cosmetic chemist and science educator, here to explain how beauty products work, debunk myths, and help you make smarter decisions about your skincare, hair and makeup!

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Article with more info and full references: labmuffin.com/does-retinol-work-skincare-science-s…

📖 Key references
www.mdedge.com/podcasts/dermatology-weekly/looking…
doi.org/10.1177/1740774515625964
doi.org/10.1016/s0190-9622(98)70437-2
doi.org/10.1111/j.1600-0625.1998.tb00299.x
doi.org/10.1016/S0021-9258(20)30065-X
Full reference list: labmuffin.com/does-retinol-work-skincare-science-s…

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All Comments (21)
  • @DaniL-hr9xo
    From a fellow scientist, it's so cool to see a video like this where you don't always talk about the main topic (retinol), but you also explain how scientific studies and publications work!! ❤🙏🏻
  • @GlamorousGamine
    Loved the statement that “only ingredients with robust clinical evidence work” is bad science. I’ll always remember the joke that there’ve been no peer reviewed clinical trials that parachutes decrease your risk of death while sky diving.
  • @wallycola5653
    Well done! Simultaneously informative, funny, and unhinged. Person having a manic episode in front of a cork board is a really good look for you
  • @_oaktree_
    Oh my god, as a librarian your section on how to search for and understand a study gave me life! I've taught these research methodologies and evaluation techniques to so many undergrads and it just gives me such pleasure to see this out in the wild, as it were :) And in the interest of helping consumers make scientifically-informed decisions!
  • @miriam8376
    I’m a rhetoric teacher and I ADORE seeing you address all the important elements in finding reliable research and how that is crucial to drawing sound, evidence-based conclusions. I’m going to show my students this video as an example of what ethical and reliable YouTube essays should aim for.
  • @noa-ix9pe
    I never thought this much information could be crammed into my brain in such a short amount if time in such a fun way, mind blown, my bio teacher could never😶
  • @Neiyk00
    Retinol worked so well for me. My skin was a disaster before using it. Now, after 2 years I literally get compliments about my skin. However, it’s a long term solution and definitely requires consistency to work.
  • @who-is-eva
    As a baby dermatologist (just started my first job last month yay) and a skincare nerd (who used to have terrible acne), your channel is such a well of knowledge for me, i think i love you
  • @pedrokass2973
    you deserve an award for your effort teaching science with common sense and creativity. Confession: I sent a message to youtube to tell them how extraordinary your videos are. Dr. Wong you're an excellent chemistry youtuber/teacher and not bad actress, brava! Claps in form of likes please.
  • @prismological
    More Corkboard Michelle please. It’s fantastic energy
  • @khadinewarrick
    This is the sort of content I hope for when some Youtubers preface their videos by saying they've done "research" into a certain topic, specifically those that tout their content as "educational". Really an excellent video! It was super informative while also being easy to follow and entertaining. Thank you! I learned a lot!
  • @blackrosenuk
    We need more cork board Michelle! Seriously, thank you! You have a talent to make things educational, informative, interesting, and funny. Your smarts and hard work really shine in this video :)
  • @skinny0ne
    wow your studies/trials explanation was amazing. I’ve never heard anyone explain it this well and with passion!
  • @evan-vd4fu
    you are such a fantastic science communicator! such an underrated and important skill when research is constantly being twisted and misrepresented in media.
  • One of the best videos in the YouTube skincare game! I loved watching this and learning about the practicalities of research. Thank you!!!!
  • @jozefwoo8079
    I've never been interested in cosmetics but this is such a thorough and interesting insight into it. I'm always delighted to be shown the hidden complexities behind a topic. This is the kind of quality most information should be! Congrats!
  • @markzeddo6033
    It was so great to get so much context about the usage of retinol: about the publishing ecosystem in both academia and industry, as well as how to interpret the studies that there are, even though there aren't clinical trials. Also, the use of the corkboard was perfect!
  • This video is pure GOLD! As expected from the queen! Looking forward to more videos like this on other ingredients. Lots of love 🥰
  • Excellent video!! So educational but still fun and not dry or too long! Wish more of my professors had been like you!
  • @Sigurjon543
    Michelle your scientific communication skills are incredible and some of the best I’ve ever seen!