Evolution of human genes and the origin of agriculture

Coming from a family that believes that the world was only started 5000 years ago I can def say thank you for this content. Intuitive but still explains the subject matter. Not academic and condescending like some lectures. World needs more vids like this

I love that you go beyond just superficially mentioning the conventional lactate dehydrogenase adaptation and explain some of the more obscure/interesting ones. Thanks for the video!

I've been watching a lot of Prof Hawk's bargain basement aesthetics video lectures and they're excellent. I've recommended them to friends interested in this stuff. They're particularly good b/c they don't require much back knowledge but still explain the complex and fascinating story of "us" so well. I really liked the Denisovan and Neanderthal lectures as well. Thx for posting!!

Muito obrigado pela excelente palestra!

Well explained. Thank you for that

It amazes me how much new info that genome discoveries have contributed to understanding our world today as well as ancient history.

Wish more people would slow down and watch these videos! 👌 Very informative and easy to understand for most individuals regardless of educational level.

Selection pressure likely peaked when it permitted a child, recently weaned because of a new sibling, to survive on cow, sheep or goat milk. Those who did not happen to have two copies of the new allele, did not survive as frequently.

Awesome video

Your videos are very informative. Totally interesting. I'm amazed there are not more thumb up marks for this video.

That was a really good presentation, thank you.

(Another) great video. The lactase persistence phenomena has always puzzled me as the detrimental phenotype of lactose intolerance (not to be confused with a milk allergy) is not terribly debilitating. Additionally, in terms of evolutionary time, dairying technology that employed bacteria to break down the lactose was effectively coincident with cattle/goat/sheep domestication Therefore it doesn't seem like the kind of thing that natural selection would have cared that much about unless there's more to the story...

At last, an excuse for my stinky armpits! Thank you John!

I really want to learn more about this. Can you give me a reading list, or tell me what university courses might have more of this information?

What a great talk! Why does it only have 15k views.

Your presentations bring together so many aspects of human evolution, such as how various species interacted. As a geologist, I am aware of very important changes in land surface since the last glacial maximum approximately 26,000 years before present. So basically, much of hominin interbreeding and cultural exchanges occurred prior to when major meltwater pulses wreaked havoc upon many cultures. Glacial and interglacial intervals and consequent sea level changes with their timing are important enough to warrant specific studies of hominins against the background of ice and ocean changes. Also, discoveries of cultural constructions along sea bottoms worldwide should help to improve archeological knowledge.

So what does gain of function gene modification fit into what you are saying?

Extremely important. I should write a book to post a comment about it.

I have a mutation that causes my insulin receptors not to function. I was a research patient for many years in Boston and I need help. I cannot get them to call me return an email even when I was living overseas I don't know if they have named it yet as I am the only one with it and dr. Jeffrey flier the dean of Harvard Medical School was the first one who began the research on me. :-(

Third of your videos i have seen now, i can just as well subscribe :)