Katherine Pollard: The Fastest Evolving Regions of the Human Genome

Published 2016-01-30
Identifying the specific mutations that make us humans is one of the greatest challenges of biology.

Join Gladstone Institutes' senior researcher Katherine Pollard in exploring the new techniques being used to discover the functions of the fastest evolving regions of the human genome and how individual DNA mutations altered these functions to make us human.

This Leakey Foundation Annual Speaker Series on Human Origins lecture took place at the Houston Museum of Natural Science on November 11, 2015.

All Comments (21)
  • @bjrockensock
    The speaker's explanation of differences among mammals at vid 16:00 is very clearly explained and helpful
  • @johnfox9169
    If this is not fascinating, nothing is!! Wonderful presentation by an excellent researcher!!
  • @grsiva
    Fantastic presentation. very clear, enjoyed watching.
  • @georgimmitev
    Good presentation. Wish my professors were this good
  • @KenDBerryMD
    Wonderful lecture, very helpful for my research!
  • @johnfraser6013
    Most excellent presentation - thank you so much ! šŸ‘šŸ‘
  • @DennisMathias
    Erie to see that tissue beating like a heart. That must have been amazing the first time it was observed.
  • Excellent. Very informative and stated at a level one could follow. I enjoyed how she hit the high points. Well done.
  • @davidhenke5603
    brilliant talk! thanks. I wonder if the "mutation clock" runs at the same rate in all species? Could mutations occur at the same rate in the highly conserved parts of the genome but are not passed to subsequent generations because most of the time they are lethal?
  • @markdstump
    43:50 15 million mutations divided by 6 million years is not about 3 million mutations/year..it's 2.5/year, or about 3/year.
  • @GaryR55
    I think she definitely went off-track when she speculated that humans may have developed speech as late as 5,000 years ago. That would have been well within the historical record. Civilization and government were arrived at by 6,000 years ago and, certainly, the beginnings of architecture and engineering, as well. So, speech would have been well-developed by then, of course. Given that art had its origins about 30,000 years ago, it is most likely that speech dates from at least 30,000 to 50,000 years ago.
  • @Skiskiski
    Question: so what are the fastestĀ evolving parts of the human genome?
  • @kforest2745
    13:57 ā€œmutations that led to fairer skin in high latitudesā€ Yeah I recall hearing about higher latitudes a long time ago