How Neurons Communicate: An Introduction to Neurotransmission and Action Potential (from PDB-101)

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RCSBProteinDataBank
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Published 2022-09-16
The billions of neurons in our nervous system are constantly communicating. The signals they send to each other are responsible for our thoughts, sensations, and actions. Learn how ions, ion channels, receptors, and neurotransmitters work together to enable the neuronal signaling process.

Learn more about neuronal signaling from PDB-101:
Opioids and Pain Signaling:    • Opioids and Pain Signaling (from PDB-...  
Neuronal Signaling and Sodium-Potassium Pump:    • Neuronal Signaling and Sodium-Potassi...  
PDB-101 resources on Cellular Signaling: pdb101.rcsb.org/browse/cellular-signaling

Story:
Ethan Cartagena (Spring 2022 RCSB PDB Intern)

Story Support:
David Goodsell (RCSB PDB), Maria Voigt, (RCSB PDB)

Animation and Video Editing:
Maria Voigt

Narration:
Ethan Cartagena

Models of the Na+/K+-ATPase Intermediate States:
William Hanson (Rutgers IQB Ph.D. Student)
All Comments (21)
  • @JL-cy1ks
    10/10, best high level description + animation out there
  • @Tierriita
    Im losing my mind at this animation. This is probably the best study tool I have access to. Thank you!
  • @hydromic2518
    Isn’t it crazy how something so simple and small can do such amazing things.
  • @user-hk5rf5ic6v
    most close to realism animation in terms of visuals. Thank you for this. really helped visualized what I read from the textbook
  • @sleeplessdev7204
    I've always wondered, how quickly do these reactions happen? For these proteins to be responsible for thoughts and muscle contractions, which seem to happen practically instantaneously from my perspective, how quick are these ions moved across the cell membrane? It's hard to wrap my mind around the scale - both in terms of how small each individual component is, and how vast their total number in even a single cell, let alone my entire body.
  • @Zeldafan1009
    Amazing to think this happens thousands of times a second
  • @jiangxu3895
    These magic and beautiful protein bots are the proof that we are robots on another level.
  • @dianasanchez7
    Incredible video. The brain, a perfect creation of God.
  • @nusiya2.08
    I didn't understand shit about this in school. This video helped me a lot. thanks man :>
  • @about-R
    👍👍👍👍👍👍👍👍👍👍